Abstracts & Clinicals

1. Brown, D., M. Canning, S. Nay, D. Yarosh. Bicyclic monoterpene diols stimulate release of nitric oxide from skin cells, increase microcirculation and elevate skin temperature. Nitric Oxide: Biology and Chemistry (in press). Email Request
2. Yarosh, D., J. Galvin, S. Nay, A. Pena, M. Canning, D. Brown. Anti-inflammatory activity in skin by biomimetic of Evodia ruteacarpa extract from traditional Chinese medicine. J Dermatol Sci. 2006 Apr; 42(1):13-21. Download (in-press version)
3. Yarosh, D., A. Pena, D. Brown. DNA repair gene polymorphisms affect cytotoxicity in the National Cancer Institute Human Tumor Cell Line Screening Panel. Biomarkers 10:188-202, 2005. Download
4. Obayashi, K., K. Kurihara, Y. Okano, H. Masaki and D.B. Yarosh. L-ergothioneine scavenges superoxide and singlet oxygen and suppresses TNFa and MMP-1 expression in UV-irradiated human dermal fibroblasts. J. Cosmet. Sci. 56:17-27, 2005. Download
5. Hellemans, L., H. Corstjens, A. Neven, L. Declercq, and D. Maes. Antioxidant Enzyme Activity in Human Stratum Corneum Shows Seasonal Variation with an Age-Dependent Recovery. J Invest Dermatol 120:434, 2003. Email Request
6. Both, D., K. Goodtzova, D. Yarosh, D. Brown. Liposome-encapsulated ursolic acid increases ceramides and collagen in human skin cells. Arch. Dermatol. Res. 293:569-575, 2002. Download
7. Yarosh, D. Liposomes in investigative dermatology. Photodermaol Photoimmunol Photomed 17:203-212, 2001. Download
8. Thiele, J.J. Oxidative targets in the stratum Corneum. A new basis for antioxidative strategies. Skin Pharmacol Appl Skin Physiol. 2001; 14 Suppl 1:87-91. Email Request
9. Kulms, D., B. Poppelmann, D. Yarosh, T. Luger, J. Krutmann, T. Schwarz. Nuclear and cell membrane effects contribute independently to the induction of apoptosis in human cells exposed to UVB radiation. Proc. Natl. Acad. Sci. 96:7974-7979, 1999. Download
10. Vink, A.A., A.M. Moodycliffe, V. Shreedhar, S.E. Ullrich, L. Roza, D.B. Yarosh and M.L. Kripke. The Inhibition of Antigen-preventing Activity of Dendritic Cells Resulting from UV Irradiation of Murine Skin is Restored by In Vitro Photorepair of Cyclobutane Pyrimidine Dimers. Proc. Natl. Acad. Sci. USA 94:5255-5260, 1997. Download
11. Yarosh, D.B., J. Kibitel, A. O'Connor, V. Hejmadi, P. Bennett and B. Sutherland. DNA Repair Liposomes in Animutagenesis. Journal of Environmental Pathology, Toxicology and Oncology. 16:287-292, 1997. Download
12. Yarosh, D., J. Klein. The Role of Liposomal Delivery in Cutaneous DNA Repair. Advanced Drug Delivery Reviews, 18:325-333, 1996. Download
13. Hartman, P.E. (32) Ergothioneine as Antioxidant. Methods in Enzymology, Vol. 186, 1990. Download
14. Yarosh D, Boumakis S, Brown A, Canning M, Galvin J., Both D, Kraus E, O'Connor A, Brown D. Measurement of UVB-Induced DNA damage and its consequences in models of immunosuppression. Methods, 28 (1):55-62, 2002. Download
15. Yarosh D, Both D, Brown D. Liposomal ursolic acid (merotaine) increases ceramides and collagen in human skin. Horm Res, 54(5-6):318-21, 2000. Download
16. Yarosh D, Brown D. Building a Better Barrier from the Inside Out. Cosmetics & Toiletries, 118(11):47-52,2003. Download
17. Yarosh, D., M. Canning, D. Teicher, D. Brown. After sun reversal of DNA damage: enhancing skin repair. Mutation Res. 571:57-64, 2005. Download
18. Brown D.A., Canning M.T., Yarosh D.B. A Bicyclic Monoterpene Diol Mixture Stimulates Release of Nitric Oxide from Skin Cells, Increases Microcirculation and Elevates Skin Temperature. Poster presented at: 64th Annual Meeting of the American Academy of Dermatology; March 3-7, 2006; San Francisco, CA. Download
19. Yarosh D.B., Canning M.T., Nay S.L., Pena A.V., Brown D.A. Anti-inflammatory Activity in Skin by Indole Quinazoline Alkaloids from Traditional Chinese Medicine. Poster presented at: 64th Annual Meeting of the American Academy of Dermatology; March 3-7, 2006; San Francisco, CA. Download
20. Pena A.V., Canning M.T., Krutmann J., Brown D.A., Yarosh D.B. Liposome Containing OGG1 Repair Oxidative Damage in Keratinocytes and Reduce Mitochondrial Toxicity. Poster presented at: 64th Annual Meeting of the American Academy of Dermatology; March 3-7, 2006; San Francisco, CA. Download
21. Dong K.K., Damaghi N., Canning M.T., Smiles K.A., Yarosh D.B.
    Bicyclic monoterpene diols increase collagen production and decrease matrix metalloproteinase-1 in fibroblasts. Poster presented at: 65th Annual Meeting of the American Academy of Dermatology; February 2-6, 2007; Washington, DC. Download
22. Dong .K., Canning M.T., Smiles K.A., Yarosh D.B. L-ergothioneine reduces UVA340-induced hydrogen peroxide in fibroblasts more efficiently than idebenone. Poster presented at: 65th Annual Meeting of the American Academy of Dermatology; February 2-6, 2007; Washington, DC. Download

White Papers

1. DNA REPAIR
   Nay S.L., Canning M.T., Pena A.V., Damaghi N., Smiles K.A., Yarosh D.B. Remergent DNA Repair Formula for Combating Photoaging. Download
2. BARRIER REPAIR
   Smiles K.A., Walfield A.M., Yarosh D.B. Remergent Barrier Repair Formula Restores Many Aspects of Skin Health. Download
3. MICROCIRCULATION THERAPY
   Canning M.T., Dong K.K., Damaghi N., Smiles K.A., Yarosh D.B. Remergent Microcirculation Therapy Stimulates Localized Blood Flow in the Skin. Download
4. REMERGENT™ HQ [HYDROQUINONE USP 4%]
   Dong K.K., Canning M.T., Smiles K.A., Yarosh D.B. Remergent HQ Is a Prescription-Strength Hydroquinone Cream for Hyperpigmentation Challenges. Download
5. SAFETY TESTING
   Safety Testing of Remergent™ Skin care Products. Download